tauroursodeoxycholic acid sodium salt
tauroursodeoxycholic acid sodium salt
CAS: 35807-85-3
Molecular Formula: C26H44NNaO6S
tauroursodeoxycholic acid sodium salt - Names and Identifiers
tauroursodeoxycholic acid sodium salt - Physico-chemical Properties
| Molecular Formula | C26H44NNaO6S |
| Molar Mass | 521.69 |
| Melting Point | 173-175°C |
| Specific Rotation(α) | +40～+50°(D/20℃) |
| Solubility | DMSO (Slightly, Heated), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
| Appearance | Solid |
| Color | Off-White to Pale Beige |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| MDL | MFCD00065451 |
| In vitro study | In Vitro, tauroussodeoxycholate exhibited protective and reversal effects on 17βEG-induced cVA-of-CLF damage. In Mz-ChA-1 cholangiocarcinoma cells, taurousodeoxycholate inhibits bile acid-induced apoptosis via β1-integrin-mediated camped formation in isolated rat hepatocytes. |
| In vivo study | In rats with phalloidin-induced bile obstruction, taurousodeoxycholate (360 μmol/kg, I. v.) significantly inhibits the decrease in bile flow and increases the activity of serum alkaline phosphatase, leucine aminopeptidase and alanine aminotransferase, as well as the concentration of cholesterol, phospholipids and bile acids. |
tauroursodeoxycholic acid sodium salt - Risk and Safety
| WGK Germany | 2 |
| RTECS | KI7372500 |
tauroursodeoxycholic acid sodium salt - Reference
| Reference Show more | 1. Cao Yan, Song Qingqing, Li Jun, etc. Analysis of chemical constituents of bile acids in yak bile [J]. Chinese Journal of Traditional Chinese Medicine, 44 Vol. 12,, pp. 2538-2543, MEDLINE ISTIC PKU CSCD CA BP, 2019. |
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